Curcumin BP

CurcuminBPCurcumin is a pigment from the Indian spice, turmeric, which gives curry its yellow color. Turmeric has been used as both food and medicine in Asia for thousands of years. Recent research has made the herb increasingly popular in Western herbalism as an anti-inflammatory remedy for conditions like arthritis and as a remedy for digestive and liver problems.

CurcuminBP is a formula that blends a standardized extract of curcumin from turmeric and black pepper. Each capsule contains 550 mg of turmeric extract that is 95% curcuminoids. The black pepper aids the assimilation of the curcumin, which can be poorly absorbed. Here is a summary of some of the potential health benefits of CurcuminBP.

Anti-Inflammatory and Joint Remedy

turmericCurcumin is a very potent anti-inflammatory. It inhibits activity of the transcription factor  NF-kB, a pro-inflammatory messenger. Clinical research suggests it can be a valuable remedy in treating rheumatoid arthritis, osteoarthritis and other inflammatory conditions.

For instance, in a study of 18 patients with rheumatoid arthritis, taking 1200 mg of curcumin daily was as effective as taking 300 mg per day of phenylbutazone, a non-steroidal anti-inflammatory drug. Curcumin was effective in reducing morning stiffness and joint swelling. In another study of curcmin’s effects on arthritis, mice fed curcumin displayed less infiltration of immune cells in the joints, less synovial hyperplasia, and less cartilage destruction and bone hyperplasia than control mice.

In a human clinical trial using turmeric for osteoarthritis, it was shown that taking a 500 mg turmeric extract twice daily significantly reduced pain and improved functionality. The study involved eight weeks of treatment in patients with osteoarthritis of the knee. Patients taking turmeric extract also had significantly reduced usage of analgesics and NSAIDs. The extract used in this study was standardized to contain 20% curcuminoids (providing 75% curcumin). CurcuminBP is much stronger than the remedy used in this study.

Digestive and Liver Remedy

Liver-in-bodyTurmeric is approved in Germany as a prescription medication for a variety of digestive disorders. Curcumin stimulates the flow of bile from the gallbladder, which aids digestion and assimilation of fats.  It can be helpful for gallstones and pain in the gallbladder. It increases mucus production in the stomach and has been shown to help ulcers to heal.  It can also relieve symptoms of heartburn, gastritis and dyspepsia.

Curcumin has hepatoprotective properties and aids liver detoxification. It increases glutathione levels and glutathione-S-transferase activity, which gives it antioxidant properties.  This is not surprising, since turmeric has long been used in both TCM (Traditional Chinese Medicine) and Ayurveda (traditional Indian medicine) as a tonic to the liver.

Antioxidant Properties

Curcumin has a powerful antioxidant action. It appears to interfere with the synthesis of pro-inflammatory eicosanoids (chemical messengers).  It acts as a free radical scavenger, inhibiting peroxidation of lipids (fats) and protecting nervous tissue from toxins like lead and other heavy metals.  The research suggests that curcumin’s antioxidant action may help to prevent certain cancers, Alzheimer’s disease and cardiovascular conditions.

Brain and Memory Benefits

brain2Several studies have shown that curcumin has a positive effect on the brain and nervous system.  It has been found to help protect the brain in injury and to reduce the risk of stroke.  In one animal study, curcumin was shown to protect against toxicity and impairment of mental ability caused by an amyloid-protein infusion. Another study found that curcumin shrank the size of plaques and reduced neurite dystrophy in an Alzheimer mouse model.

Cardiovascular Benefits

A study using a transgenic animal model indicated that curcumin diminished plaque formation and overall inflammation in the cardiovascular system.  It has been shown to have a synergistic effect with fish oil to improve blood flow and protect against cognitive deficits.

Anti-Cancer Activity

In one study, curcumin induced apoptosis (cell death) in cancer cells without cytotoxic effects on healthy cells.  In an animal study, curcumin inhibited the growth of cancer cells in the stomach, liver and colon as well as oral cancers.

Suggested Use

Take one CurcuminBP capsule twice daily. Curcumin is more easily absorbed when taken with fats and can be taken with Super Omega-3 EPA or other fats for better assimilation.

Selected References

“International Journal of Clinical Pharmacology, Therapy and Toxicology,” Evaluation of Anti-Inflammatory Property of Curcumin in Patients With Postoperative Inflammation; R.R. Satoskar, June 1986
Maheshwari RK, et al. (2006). Multiple Biological Activities of Curcumin: A short review. Life Sciences, Mar. 27, 78(18): 2081-2087.
Chopra A, et al. (2004). A 32-week randomized, placebo-controlled clinical evaluation of RA-11, an ayurvedic drug, on osteoarthritis of the knees. Journal of Clinical Rheumatology. Oct. 10 (5): 236-245.

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